Extended pointers for memory protection in single address space systems

With reference to a single address space paradigm of memory addressing, we identify a set of mechanisms aimed at preserving the integrity of the virtual space of a given process from erroneous or fraudulent access attempts originated from other processes. These mechanisms guarantee a level of protection that is, in many respects, superior to that of a traditional multiple address space environment. We introduce extended pointers as a generalization of the concept of a memory address, which includes a password and an access authorization. A universally known, parametric one-way function is used to assign passwords. A specialized address translation circuitry supports memory reference and protection at the hardware level. A small set of protection primitives forms the process interface of the protection system. An indication of the flexibility of the proposed protection paradigm is given by applying extended pointers to the solution of a variety of protection problems

Neural networks for driver behavior analysis

The proliferation of info-entertainment systems in nowadays vehicles has provided a really cheap and easy-to-deploy platform with the ability to gather information about the vehicle under analysis. With the purpose to provide an architecture to increase safety and security in automotive context, in this paper we propose a fully connected neural network architecture considering positionbased features aimed to detect in real-time: (i) the driver, (ii) the driving style and (iii) the path. The experimental analysis performed on real-world data shows that the proposed method obtains encouraging results

Use of psychiatric inpatient services by heavy users: Findings from a national survey in Italy

Indagine epidemiologica nazionale sull'uso dei SPDC da parte dei pazienti più gravi sul versante dell'uso dei Serviz

The CUORE Cryostat: A 1-Ton Scale Setup for Bolometric Detectors

The cryogenic underground observatory for rare events (CUORE) is a 1-ton scale bolometric experiment whose detector consists of an array of 988 TeO2 crystals arranged in a cylindrical compact structure of 19 towers. This will be the largest bolometric mass ever operated. The experiment will work at a temperature around or below 10 mK. CUORE cryostat consists of a cryogen-free system based on pulse tubes and a custom high power dilution refrigerator, designed to match these specifications. The cryostat has been commissioned in 2014 at the Gran Sasso National Laboratories and reached a record temperature of 6 mK on a cubic meter scale. In this paper, we present results of CUORE commissioning runs. Details on the thermal characteristics and cryogenic performances of the system will be also given.Comment: 7 pages, 2 figures, LTD16 conference proceedin

Model Checking to Improve Precision of Design Pattern Instances Identification in OO Systems

In the last two decades some methods and tools have been proposed to identify the Design Pattern (DP) instances implemented in an existing Object Oriented (OO) software system. This allows to know which OO components are involved in each DP instance. Such a knowledge is useful to better understand the system thus reducing the effort to modify and evolve it. The results obtained by the existing methods and tools can suffer a lack of completeness or precision due to the presence of false positive/negative. Model Checking (MC) algorithms can be used to improve the precision of DP's instances detected by a tool by automatically refining the results it produces. In this paper a MC based technique is defined and applied to the results of an existing DPs mining tool, called Design Pattern Finder (DPF), to improve the precision by verifying automatically the DPs instances it detects. To verify and assess the feasibility and the effectiveness of the proposed technique, we carried out a case study where it was applied on some open source OO systems. The results showed that the proposed technique allowed to improve the precision of the DPs instances detected by the DPF tool

The CUORE cryostat: an infrastructure for rare event searches at millikelvin temperatures

The CUORE experiment is the world's largest bolometric experiment. The detector consists of an array of 988 TeO2 crystals, for a total mass of 742 kg. CUORE is presently taking data at the Laboratori Nazionali del Gran Sasso, Italy, searching for the neutrinoless double beta decay of 130Te. A large custom cryogen-free cryostat allows reaching and maintaining a base temperature of about 10 mK, required for the optimal operation of the detector. This apparatus has been designed in order to achieve a low noise environment, with minimal contribution to the radioactive background for the experiment. In this paper, we present an overview of the CUORE cryostat, together with a description of all its sub-systems, focusing on the solutions identified to satisfy the stringent requirements. We briefly illustrate the various phases of the cryostat commissioning and highlight the relevant steps and milestones achieved each time. Finally, we describe the successful cooldown of CUORE

Measurement of the Two-Neutrino Double Beta Decay Half-life of 130^{130}Te with the CUORE-0 Experiment

We report on the measurement of the two-neutrino double beta decay half-life of $^{130}$Te with the CUORE-0 detector. From an exposure of 33.4 kg$\cdot$y of TeO$_2$, the half-life is determined to be $T_{1/2}^{2\nu}$ = [8.2 $\pm$ 0.2 (stat.) $\pm$ 0.6 (syst.)] $\times$ 10$^{20}$y. This result is obtained after a detailed reconstruction of the sources responsible for the CUORE-0 counting rate, with a specific study of those contributing to the $^{130}$Te neutrinoless double beta decay region of interest.Comment: Corrected typo in section 9: 3.43E5 Bq/kg should have read 3.43E-5 Bq/k

Analysis Techniques for the Evaluation of the Neutrinoless Double-Beta Decay Lifetime in 130^{130}Te with CUORE-0

We describe in detail the methods used to obtain the lower bound on the lifetime of neutrinoless double-beta ($0\nu\beta\beta$) decay in $^{130}$Te and the associated limit on the effective Majorana mass of the neutrino using the CUORE-0 detector. CUORE-0 is a bolometric detector array located at the Laboratori Nazionali del Gran Sasso that was designed to validate the background reduction techniques developed for CUORE, a next-generation experiment scheduled to come online in 2016. CUORE-0 is also a competitive $0\nu\beta\beta$ decay search in its own right and functions as a platform to further develop the analysis tools and procedures to be used in CUORE. These include data collection, event selection and processing, as well as an evaluation of signal efficiency. In particular, we describe the amplitude evaluation, thermal gain stabilization, energy calibration methods, and the analysis event selection used to create our final $0\nu\beta\beta$ decay search spectrum. We define our high level analysis procedures, with emphasis on the new insights gained and challenges encountered. We outline in detail our fitting methods near the hypothesized $0\nu\beta\beta$ decay peak and catalog the main sources of systematic uncertainty. Finally, we derive the $0\nu\beta\beta$ decay half-life limits previously reported for CUORE-0, $T^{0\nu}_{1/2}>2.7\times10^{24}$ yr, and in combination with the Cuoricino limit, $T^{0\nu}_{1/2}>4.0\times10^{24}$ yr.Comment: 18 pages, 18 figures. (Version 3 reflects only minor changes to the text. Few additional details, no major content changes.

Search for Neutrinoless Double-Beta Decay of 130^{130}Te with CUORE-0

We report the results of a search for neutrinoless double-beta decay in a 9.8~kg$\cdot$yr exposure of $^{130}$Te using a bolometric detector array, CUORE-0. The characteristic detector energy resolution and background level in the region of interest are $5.1\pm 0.3{\rm~keV}$ FWHM and $0.058 \pm 0.004\,(\mathrm{stat.})\pm 0.002\,(\mathrm{syst.})$~counts/(keV$\cdot$kg$\cdot$yr), respectively. The median 90%~C.L. lower-limit sensitivity of the experiment is $2.9\times 10^{24}~{\rm yr}$ and surpasses the sensitivity of previous searches. We find no evidence for neutrinoless double-beta decay of $^{130}$Te and place a Bayesian lower bound on the decay half-life, $T^{0\nu}_{1/2}>$~$2.7\times 10^{24}~{\rm yr}$ at 90%~C.L. Combining CUORE-0 data with the 19.75~kg$\cdot$yr exposure of $^{130}$Te from the Cuoricino experiment we obtain $T^{0\nu}_{1/2} > 4.0\times 10^{24}~\mathrm{yr}$ at 90%~C.L.~(Bayesian), the most stringent limit to date on this half-life. Using a range of nuclear matrix element estimates we interpret this as a limit on the effective Majorana neutrino mass, $m_{\beta\beta}< 270$ -- $760~\mathrm{meV}$.Comment: 6 pages, 5 figures, updated version as published in PR

Antipsychotic prescribing for vulnerable populations: a clinical audit at an acute Australian mental health unit at two-time points

Background: Antipsychotics are recognised as a critical intervention for schizophrenia and bipolar disorder. Guidelines globally endorse the routine practice of antipsychotic monotherapy, at the minimum effective dose. Even in treatmentresistant schizophrenia, clozapine use is endorsed before combining antipsychotics. This aim of this study was to review antipsychotic polytherapy alone, high-dose therapy alone, polytherapy and highdose prescribing patterns in adults discharged from an inpatient mental health unit at two time-points, and the alignment of this prescribing with clinical guideline recommendations. Additionally, associations with polytherapy and high-dose antipsychotic prescribing, including patient and clinical characteristics, were explored. Methods: A retrospective clinical audit of 400 adults (200 patients at two different time-points) discharged with at least one antipsychotic. Preliminary findings and education sessions were provided to physicians between Cohorts. Outcomes (polytherapy alone, high-dose therapy alone, polytherapy and high-dose therapy) were compared between study Cohorts using chi-squared and rank-sum tests. Associations between outcomes and covariates were assessed using multivariable logistic regression. Results: Most patients (62.5%) were discharged on a single antipsychotic within the recommended dose range. There was a clear preference for prescribing second generation antipsychotics, and in this respect, prescribing is aligned with current evidence-based guidelines. However, sub-optimal prescribing practices were identified for both Cohorts in relation to polytherapy and high-dose antipsychotic rates. Involuntary treatment, frequent hospitalisations and previous clozapine use significantly increased the risk of all three prescribing outcomes at discharge. Conclusions: In a significant minority, antipsychotic prescribing did not align with clinical guidelines despite increased training, indicating that the education program alone was ineffective at positively influencing antipsychotic prescribing practices. Further consideration should be given when prescribing antipsychotics for involuntary patients, people with frequent hospitalisations, and those who have previously trialled clozapine